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GHS Category - Carcinogenicity
Posted Date:2022/8/19
GHS Definition:
Carcinogens are substances or mixtures that can cause cancer or increase the incidence of cancer. Substances and mixtures that induce benign and malignant tumors in properly conducted experimental studies in animals are also considered to be putative or suspected human carcinogens, unless there is conclusive evidence that the mechanism of tumor formation is not relevant to humans.
Substances or mixtures are classified by their carcinogenic hazard, by their very nature, and do not provide information on the level of human carcinogenic risk that may arise from the use of the substance or mixture.
Carcinogenicity Criteria:
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Category
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Standard
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Category 1
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Known or presumed human carcinogens
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Category 1 A
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Known to be carcinogenic to humans; the classification of the substance is based primarily on human evidence.
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Category 1 B
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Assumed to be carcinogenic to humans; substances are classified based primarily on animal evidence.
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Category 2
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Suspected human carcinogen
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Examples of carcinogenic chemicals:
▪4-Aminobiphenyl
▪Chordane
▪Octachlorocampene
▪Octabromobiphenyl
▪benzofuran
▪1,2-Benzenediol
▪Vinylbenzene
Carcinogenicity labelling and classification:
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Classification
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Label
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Hazard statement code
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Hazard category
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Hazard classification
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Pictograms
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Signal word
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Hazard statement
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GHS
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United Nations Model Regulations
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Carcinogenicity
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1
(Subclasses 1A and 1B)
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None
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Danger
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May cause cancer
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H350
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2
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None
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Warn
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Suspected of causing cancer
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H351
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